Topical anesthesia entails the depositing of an anesthetic product in contact with the structure to be anesthetized without having to resort to taking an injection. It is developed primarily for the eye and the skin.
No one wants to go through pain if he or she can help it, yet pain is a part of life. Of course, you don’t need to suffer – you can find many ways that you can combat all sorts of pain that plague your body. Pills, topical treatments, and more are commonly available. Having so many things that can affect you during beauty procedures or aesthetic treatments, you are going to need some of these medicinal items on hand.
Topical anesthetics are medications that numb and subdue the sensation of pain in the area to which they are administered. They are in the form of gels, ointments, solutions, creams, eye drops, gels or sprays and used in regions such as the skin, the eyes or the nose.
Topical anesthetics are applied to the skin to alleviate pain caused by sunburn or other minor fire injuries, bug bites, minor cuts, or before dressing changes when wounds are extensive. They may also be used before vaccination or any other procedure that requires needle insertion.
It is a good idea to have on hand pain relief gel, which has many uses and comes in many different varieties. These topical gels can work wonders on skin, sore and aching muscles as well as for problematic joints.
The basic method of action of topical anesthetics is the blocking of sodium channels voltage and time-dependent. They bind to a specific receptor site, located within the pores that constitute the sodium channels of nerve fibers. They block the ionic movements through these pores and modify the action potential, preventing, on the one hand, the penetration of Na + inside the fiber (progressive reduction of the amplitude of the action potential, slowing of its speed conduction and elevation of the depolarization threshold). It also decreases the conduction of the impulse along the nerve fiber (elongation of the refractory period).
MECHANISMS OF ACTION OF DIFFERENT MOLECULES
Topical anesthesia reversibly inhibits nerve conduction without alteration of the nerve. The inhibition appears rapidly and for longer or shorter periods depending on the products and the concentrations applied. The extent of the area made insensitive to pain depends on the means of administration of the topical anesthetic, either at the level of the nerve endings or at the level of a nerve trunk, for example.
They work at the level of the neuronal membrane by meddling with the process of excitation and conduction. The anesthetic passes the axon membrane, rich in lipids, in the form of a base. It then takes up a cationic form on the internal face of the neuron where the acidic pH level that is an all-time high. At this point, there is a blockage of nerve conduction by reducing the membrane permeability to sodium ions that take place during the depolarization point. As the progress of the anesthetic action along the nerve increases, the outset of excitability increases and the conduction period adds. This is wholly obstructed from some concentration of topical anesthetic.
The nerve fibers are unequally sensitive to the action of local anesthetics: they disappear in order: the painful, thermal, tactile sensations.
PREVENTING PAIN WITH ANESTHETIC CREAM
Faced with the pain that can represent a small intervention, such as a dermatological intervention, it is now possible to prevent this pain by applying anesthetic cream. Anesthetic creams are now used with ease, to be applied a few hours before the particular moment to come, for greater efficiency. Back on the composition of anesthetic creams, Anestop in particular!
Anestop cream, an anesthetic cream
Anestop cream is nowadays prescribed by the doctors or the nurses who wish to be able to avoid unnecessary pain to their patients. The latter reports very appreciable effectiveness, allowing to anesthetize the skin locally. People wishing to approach a blood test, a small dermatological intervention in a more serene, more relaxed, assured not to have to feel the pain to come!
Anestop is composed of Dexpanthenol, Amethocaine, Propitocaine, and Lignocaine, these two active ingredients then make it possible to benefit from an effective anesthetic cream, which makes it possible to block the stimuli coming from the nervous system. The action of the Anestop is fast when it can spread for nearly an hour, blocking any pain after surgery.
When should I apply Anestop?
In general, it is up to physicians to refer their patients to the use of anesthetic cream if necessary. Usable for adults as well as for children (except in the context of a contraindication), the Anestop anesthetic cream is mainly prescribed in the following cases:
- Taking blood bites to sensitive people
- Plan subcutaneous injection
- Diverse Dermatological intervention
Apply Anestop 30 minutes before the operation, in the area of the skin concerned, making sure to apply a thick layer.
BENEFITS OF TOPICAL ANESTHESIA
In addition to home remedies and alternative medicine, topical cream can help to alleviate severe pain within seconds. The application method used also allows the cream to go directly to the source of the pain so that one gets immediate relief. Topical creams are also convenient, and they work by sending the active ingredients into the skin where they can begin working to provide relief.